Advanced Life Support (ALS) Level 3 (VTQ)

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Diazepam: Understanding Its Forms and Applications

Overview of Diazepam

Exploring Diazepam Forms, Indications, and Cautionary Considerations

  • Diazepam Presentations: Diazepam is commonly available in ampules, each containing 10 milligrams of diazepam in a 2 millilitre oil-in-water emulsion. It is also accessible as a rectal tube with diazepam solution options of 2.5 milligrams, 5 milligrams, or 10 milligrams.
  • Contraindications: There are no absolute contraindications for diazepam.
  • Indications: Diazepam is indicated for specific conditions, including:
    • Status Epilepticus: In cases of seizures lasting longer than five minutes.
    • Eclamptic Seizures: When seizures extend beyond two to three minutes or recur.
    • Symptomatic Cocaine Toxicity: Manifesting as hypertension, seizures, or chest pain.
  • Mode of Action: Diazepam acts as a sedative or anticonvulsant by depressing the central nervous system.
  • Dosage Considerations: Exercise caution when determining dosages, taking into account recent doses to calculate the maximum cumulative dose of diazepam.
  • Combination Precautions: Be cautious when using diazepam in conjunction with alcohol, CNS depressants, or antidepressants, as these combinations may increase the risk of side effects.