Advanced Life Support (ALS) Level 3 (VTQ)

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Aspirin Use in Myocardial Infarctions

How Aspirin Works

Understanding its Mechanism of Action

Thromboxane A2 Blocker: Aspirin inhibits the formation of thromboxane A2, preventing platelet aggregation and reducing clot formation.

Benefits in Myocardial Infarctions

Reducing Mortality and Re-infarction Risk

Usage: Administer a single 300-milligram tablet in suspected myocardial infarctions.

Chew and Swallow: The tablet should be chewed and swallowed.

Safe Usage

Considerations and Potential Risks

  • Appropriate Dosage: Typically a 300-milligram tablet.
  • Antiplatelet Action: Acts as an antiplatelet agent to reduce clot formation.
  • Safe for Various Conditions: Benefits outweigh risks; can be given to patients with asthma, kidney or liver failure, ulcers, or those on anticoagulants.
  • Safe for Pregnant Women: Considered safe for pregnant ladies.

Side Effects and Contraindications

Understanding Risks and Who Should Avoid It

Side Effects: Gastric bleeding and potential wheezing in asthmatics.

  • Contraindications: Do not administer to those with aspirin allergies, children under 16, patients with active gastrointestinal bleeding, haemophilia, blood clotting disorders, or hepatic disease.
  • Reye's Syndrome Risk: Contraindicated in children under 16 due to the rare risk of Reye's syndrome, a condition with a high mortality rate affecting the liver and brain.